1.Jiang Y, Jin X, Chi Z, Bai Y, Manthiram K, Mudd P, Zhu K, Wang L, Schwartzberg PL, Han Y, Gao X, Lu L*, Xu Q*. Protein phosphatase 2A propels follicular T helper cell development in lupus. J Autoimmun. 2023 Apr;136:103028. doi: 10.1016/j.jaut.2023.103028. 2023 Mar 29. PMID: 37001432.
2.Jin X, Han Y, Wang JQ, Lu L*.CAR-T cell therapy: new hope for systemic lupus erythematosus patients.Cell Mol Immunol. 2021 Dec;18(12):2581-2582. doi: 10.1038/s41423-021-00787-5. 2021 Nov 4.PMID: 34737415
3.Wu L, Xue Z, Jin S, Zhang J, Guo Y, Bai Y, Jin X, Wang C, Wang L, Liu Z, Wang JQ, Lu L* and Liu W*.huARdb: human Antigen Receptor database for interactive clonotype-transcriptome analysis at the single-cell level.Nucleic Acids Res. 2022 Jan 7;50(D1):D1244-D1254. doi: 10.1093/nar/gkab857.7.PMID: 34606616
4.Zhu K, Jin X, Cui Z, Chen S, Wu S, Sloan R, Lin X, Neculai D, Wang D, Hu H, Lu L*.Priming of NLRP3 inflammasome activation by Msn kinase MINK1 in macrophages.Cell Mol Immnol.2021 Oct;18(10):2372-2382. doi: 10.1038/s41423-021-00761-1. Epub 2021 Sep 3.
5.Lu L*.Mobilizing ER IP3 receptors as a mechanism to enhance calcium signaling. Cell Mol Immunol.2021 Sep;18(9):2284-2285.doi: 10.1038/s41423-021-00725-5.Epub 2021 Jul 12.PMID: 34253857
6.Shytikov D, Rohila D, Li D, Wang P, Jiang M, Zhang M, Xu Q, Lu L*.Functional Characterization of Ly49+CD8 T-Cells in Both Normal Condition and During Anti-Viral Response. Front Immunol. 2021 Jan 7;11:602783. doi: 10.3389/fimmu.2020.602783. eCollection 2020.PMID: 33488602
7.Jin X, Xu Q, Pu C, Zhu K, Lu C, Jiang Y, Xiao L, Han Y*, Lu L*. Therapeutic efficacy of anti-CD19 CAR-T cells in a mouse model of systemic lupus erythematosus. Cell Mol Immunol. 2021 Aug;18(8):1896-1903. doi: 10.1038/s41423-020-0472-1. Epub 2020 May 29.PMID: 32472023
8.Lyu J, Wang L, Lu L*. Thymocyte selection: From signaling to epigenetic regulation. Adv Immunol. 2019;144:1-22. doi: 10.1016/bs.ai.2019.08.005. Epub 2019 Oct 15.PMID: 31699214
9.Lyu J, Wang P, Xu T, Shen Y, Cui Z, Zheng M, Fu G, Lu L*. Thymic-specific regulation of TCR signaling by Tespa1. Cell Mol Immunol.2019 Dec;16(12):897-907. doi: 10.1038/s41423-019-0259-4. Epub 2019 Jul 17.PMID: 31316154
10.Zheng M, Li D, Zhao Z, Shytikov D, Xu Q, Jin X, Liang J, Lou J, Wu S, Wang L, Hu H, Zhou Y, Gao X*, Lu L*. Protein phosphatase 2A has an essential role in promoting thymocyte survival during selection. 2019 Jun 18;116(25):12422-12427. doi:10.1073/pnas.1821116116. Epub 2019 May 31.PMID: 31152132
11.Xu Q, Jin X, Zheng M, Rohila D, Fu G, Wen Z, Lou J, Wu S, Sloan R, Wang L, Hu H, Gao X*, Lu L*. Phosphatase PP2A is essential for TH17 differentiation. Proc Natl Acad Sci U S A. 2019 Jan 15;116(3):982-987. doi: 10.1073/pnas.1807484116. Epub 2018 Dec 28.PMID: 30593560
12.Lou J, Li X, Huang W, Liang J, Zheng M, Xu T, Lyu J, Li D, Xu Q, Jin X, Fu G, Wang D, Lu L.* SNX10 promotes phagosome maturation in macrophages and protects mice against Listeria monocytogenes infection. Oncotarget, 2017 Jul 27;8(33):53935-53947. doi: 10.18632/oncotarget.19644. eCollection 2017 Aug 15.PMID: 28903313
13.Liang J, Lyu J, Zhao M, Li D, Zheng M, Fang Y, Zhao F, Lou J, Guo C, Wang L, Wang D, Liu W*, Lu L*. Tespa1 regulates T cell receptor-induced calcium signals by recruiting inositol 1,4,5-trisphosphate receptors.Nat Commun. 2017 Jun 9;8:15732. doi: 10.1038/ncomms15732.PMID: 28598420
14.Fu G, Xu Q, Qiu Y, Jin X, Xu T, Dong S, Wang J, Ke Y, Hu H, Cao X, Wang D, Cantor H, Gao X and Lu L*. Suppression of Th17 cell differentiation by misshapen/NIK-related kinase MINK1. J Exp Med. 2017 May 1;214(5):1453-1469. doi: 10.1084/jem.20161120. Epub 2017 Apr 11.PMID: 28400474
15.Yue M, Luo D, Yu S, Liu P, Zhou Q, Hu M, Liu Y, Wang S, Huang Q, Niu Y, Lu L*, Hu H*. Misshapen/ NIK-related Kinase (MINK1) is involved in platelet function, hemostasis and thrombus formation. BLOOD. 2016 Feb 18;127(7):927-37. doi: 10.1182/blood-2015-07-659185. Epub 2015 Nov 23.PMID: 26598717
16.Yue Y, Huang W, Liang J, Guo J, Ji J, Yao Y, Zheng M, Cai Z, Lu L*, Wang J*. IL4I1 Is a Novel Regulator of M2 Macrophage Polarization That Can Inhibit T Cell Activation via L-Tryptophan and Arginine Depletion and IL-10 Production. PLoS One. 2015 Nov 24;10(11):e0142979. doi: 10.1371/journal.pone.0142979. eCollection 2015.PMID: 26599209
17.Wang D*, Zheng M, Qiu Y, Guo C, Ji J, Lei L, Zhang X, Liang J, Lou J, Huang W, Dong B, Wu S, Wang J, Ke Y, Cao X, Zhou YT andLu L*, Tespa1 negatively regulates FcεRI-mediated signaling and the mast cell-mediated allergic response. J Exp. Med. 2014 Dec 15;211(13):2635-49. doi: 10.1084/jem.20140470. Epub 2014 Nov 24.PMID: 25422497
18.Lu L* and Wang J*, One way to pathogenesis, many ways to homeostasis. Cellular & Molecular Immunology . 2013 Jan;10(1):2-3. doi: 10.1038/cmi.2012.51. Epub 2012 Oct 29.PMID: 23103722
19.Yao Y, Han W, Liang J, Ji Jian, Wan J, Cantor H, Lu L*, Glatiramer acetate ameliorates inflammatory bowel disease in mice through the induction of Qa-1-restricted CD8+ regulatory cells. Eur. J. Immunol. 2013 Jan;43(1):125-36. doi: 10.1002/eji.201242758. Epub 2012 Nov 7.PMID: 23002042
20.Wang D, Zheng M, Lei L, Ji J, Yao Y, Qiu Y, Ma L, Lou J, Ouyang C, Zhang X, He Y, Chi J, Wang L, Kuang Y, Wang J, Cao X and Lu L*, Tespa1 is involved in late thymocyte development through the regulation of TCR-mediated signaling. Nature Immunology .2012 May 6;13(6):560-8. doi: 10.1038/ni.2301.PMID: 22561606
21.Wang D, Lou J, Ouyang C, Chen W, Liu Y, Liu X, Cao X, Wang J and Lu L*, Ras-related Protein Rab10 facilitates TLR4 signaling by promoting replenishment of TLR4 onto the plasma membrane. Proc Natl Acad Sci U S A. 2010 Aug 3;107(31):13806-11. doi: 10.1073/pnas.1009428107. Epub 2010 Jul 19.PMID: 20643919
22.Lu L, Kim H-J, Werneck M and Cantor H*, Regulation of CD8+ Treg: Interruption of NKG2A- Qa-1 interaction allows robust suppressive activity and resolution of autoimmune disease. Proc Natl Acad Sci U S A. 2008 Dec 9;105(49):19420-5. doi: 10.1073/pnas.0810383105. Epub 2008 Dec 1.PMID: 19047627
23.Lu L and Cantor H*, Generation and Regulation of CD8+ Regulatory T Cells. Cell Mol Immunol. 2008 Dec;5(6):401-6. doi: 10.1038/cmi.2008.50.PMID: 19118505
24.Lu L, Ikizawa K, Hu D, Werneck MBF, Wucherpfennig KW, and Cantor H.*, Regulation of Activated CD4+ T Cells by NK Cells via the Qa-1–NKG2A Inhibitory Pathway. Immunity .2007 May;26(5):593-604. doi: 10.1016/j.immuni.2007.03.017.PMID: 17509909
25.Lu L, Werneck M, Cantor H*. The Immunoregulatory Effects of Qa1. Immunol Rev. 2006 Aug;212:51-9. doi: 10.1111/j.0105-2896.2006.00418.x.PMID: 16903905
26.Lu L, Chen JJ. Molecular cloning and characterization of the promoter of mouse heme-regulated eIF2alpha kinase. Biochim Biophys Acta. 2002 Mar 19;1574(2):193-9. doi: 10.1016/s0167-4781(01)00281-0. PMID: 11955629.
27.Lu L, Han A, Chen J-J*. Translation Initiation Control by Heme-Regulated Eukaryotic Initiation Factor 2alpha Kinase in Erythroid Cells under Cytoplasmic Stresses” Mol. Cell. Biol. 2001 Dec;21(23):7971-80. doi: 10.1128/MCB.21.23.7971-7980.2001.PMID: 11689689
28.*Guan Z, *Lu L, Zhong Z, Liu J, Yu F, Lu S, Xin Y, Liu XY, Hong J, Zhang W*. A spontaneous recurrent seizure-related Rattus NSF gene identified by linker capture subtraction. Mol Brain Res. 2001 Feb 19;87(1):117-23. doi: 10.1016/s0169-328x(00)00286-2.PMID: 11223166
29.Lu L, Zhu J, Zheng Z, Yan M, Xu W, Sun L, Theze J, Liu X*. Jak-STAT pathway is involved in the induction of TNF-b gene during stimulation by IL-2. European Journal of Immunology 1998;28: 805-810.