22SG16，上海市曙光计划，广谱抗冠状病毒中和抗体产生和中和病毒机制研究，2023年1月-2024年12月，项目负责人

2022，国家高层次人才特殊支持计划，项目负责人

2018ZX10301403-002，国家科技部重大专项，多靶点抗高致病性流感病毒的超广谱抗体的应用性研发，2018年1月-2020年12月，课题负责人

2017ZX10202102，国家科技部重大专项，艾滋病功能性治愈策略与临床研究，2017年1月-2020年12月，课题骨干

17PJ408200，上海市浦江人才，恒河猴动物模型研究艾滋病感染过程中和抗体的产生机理，2017年7月-2019年6月，课题负责人

2022.4-至今 上海交通大学医学院附属仁济医院、上海市免疫治疗创新研究院 研究员

2017.1-2022.4 复旦大学附属上海市公共卫生临床中心 副研究员

2009.10-2016.12 美国国立卫生研究院过敏与传染病研究所 博士后

2003.9-2009.7 清华大学生物科学与技术系 博士

1999.9-2003.7 武汉大学生命科学学院 本科

1.ZL202010740319.3. 一种特异性结合冠状病毒的抗体或其抗原结合片段

2.ZL202011061756.9. 冠状病毒的特异性抗体或其抗原结合片段

3.ZL202011061736.1 冠状病毒的中和抗体或其抗原结合片段

4.ZL202011065506.2 冠状病毒的抗体或其抗原结合片段

1.Tingting Sun, Yingdan Wang, Peng Zou, Qimin Wang, Jiangyan. Liu, Wanli Liu, Jinghe Huang*, Fan Wu*. M2e specific antibodies protect against influenza PR8 virus in an isotype and route dependent manner. J Med Virol 2023. 95(4):e28721.

2.Yingdan Wang #, Xiang Zhang #, Yunping Ma #, Yanqun Wang #, Wuqiang Zhan, Qinwen Zheng, Meng Zhang, Ping Ji, Mei Liu, Qianying Liu, Tingting Sun, Tongyu Zhu, Yumei Wen, Lei Sun*, Jincun Zhao*, Fan Wu*, Zhenguo Chen*, Jinghe Huang*. Combating the SARS-CoV-2 Omicron (BA.1) and BA.2 with potent bispecific antibodies engineered from non-Omicron neutralizing antibodies. Cell Discov. 2022 Oct 7;8(1):104

3.Yingdan Wang #, Wuqiang Zhan #, Jiangyan Liu #, Yanqun Wang #, Xiang Zhang, Meng Zhang, Lin Han, Yunping Ma, Lu Lu, Yumei Wen, Zhenguo Chen, Jincun Zhao*, Fan Wu*, Lei Sun*, Jinghe Huang*. A broadly neutralizing antibody against SARS-CoV-2 Omicron variant infection exhibiting a novel trimer dimer conformation in spike protein binding. Cell Res. 2022 Jun 29;1-4

4.Yingdan Wang #, Meiqin Liu #, Yaping Shen #, Yunping Ma #, Xiang Li # , Yuanyuan Zhang #, Mei Liu #, Xing-Lou Yang #, Jun Chen #, Renhong Yan, Die Luan, Yanqun Wang, Ying Chen, Qimin Wang, Haofeng Lin, Yaning Li, Kaiyue Wu, Tongyu Zhu, Jincun Zhao, Hongzhou Lu*, Yumei Wen*, Shibo Jiang*, Fan Wu*, Qiang Zhou*, Zheng-Li Shi*, Jinghe Huang*. Novel sarbecovirus bispecific neutralizing antibodies with exceptional breadth and potency against currently circulating SARS-CoV-2 variants and sarbecoviruses. Cell Discov. 2022; 8: 36

5.Yingdan Wang#, Yunping Ma#, Yan Xu#, Jiangyan Liu#, Xiang Li, Yuyuan Chen, Yan Chen, Jun Xie, Lianbo Xiao, Zheng Xiang*, Fan Wu*, Jinghe Huang*. Resistance of SARS-CoV-2 Omicron variant to convalescent and CoronaVac vaccine plasma. Emerg Microbes Infect. 2022 Dec;11(1):424-427

6.Xiren Deng, Qimin Wang, Mei Liu, Qinwen Zheng, Fan Wu*, Jinghe Huang*. Tetrameric Neuraminidase of Influenza A Virus Is Required to Induce Protective Antibody Responses in Mice. Front Microbiol. 2021 Oct 4;12:729914

7.Fan Wu #, Su Zhao #, Bin Yu #, Yan-Mei Chen #, Wen Wang #, Zhi-Gang Song #, Yi Hu #, Zhao-Wu Tao, Jun-Hua Tian, Yuan-Yuan Pei, Ming-Li Yuan, Yu-Ling Zhang, Fa-Hui Dai, Yi Liu, Qi-Min Wang, Jiao-Jiao Zheng, Lin Xu, Edward C Holmes, Yong-Zhen Zhang*. A new coronavirus associated with human respiratory disease in China. Nature. 2020 Mar;579(7798):265-269.

8.Fan Wu*, Mei Liu, Aojie Wang, Lu Lu, Qimin Wang, Chenjian Gu, Jun Chen, Yang Wu, Shuai Xia, Yun Ling, Yuling Zhang, Jingna Xun, Rong Zhang, Youhua Xie, Shibo Jiang, Tongyu Zhu, Hongzhou Lu, Yumei Wen, Jinghe Huang*. Evaluating the Association of Clinical Characteristics With Neutralizing Antibody Levels in Patients Who Have Recovered From Mild COVID-19 in Shanghai, China. JAMA Intern Med. 2020 Oct 1;180(10):1356-1362

9.Fan Wu*, Ilnour Ourmanov, Andrea Kirmaier, Sivan Leviyang, Celia LaBranche, Jinghe Huang, Sonya Whitted, Kenta Matsuda, David Montefiori, Vanessa M Hirsch*. SIV infection duration largely determines broadening of neutralizing antibody response in macaques. J Clin Invest. 2020 Oct 1;130(10):5413-5424

10.Qimin Wang, Yulin Zhang, Peng Zou, Meixiang Wang, Weihui Fu, Jialei She, Zhigang Song, Jianqing Xu, Jinghe Huang*, Fan Wu* Self-assembly M2e-based peptide nanovaccine confers broad protection against influenza viruses. Front. Microbiol. 2020; 11:1961